Phytochemical, Antioxidant and Anti-diabetic Potentials of the Ethanol Leave Extracts of four Medicinal Plants

For many years, medicinal plants have been a resource for healing in several local communities around the world and phytochemicals them such as flavonoids, alkaloids, phenolic, tannins, terpenoids are attributed to their values. Vernonia amydalina, Senna alata, Jatropha curcas, Grewia pubescens important with immense value. In this study, phytochemical screening, antioxidant analysis potential anti-hyperglycemic properties of was investigated in-vitro. The ethanol leave extracts were subjected qualitative screening tannin, flavonoids phenol quantification. Ferric reducing power DPPH radical inhibition done by spectrophotometric method while anti-diabetic analyzed through in-vitro α-amylase α-glucosidase inhibition. Phytochemicals detected four phenolics, terpenoids, steroids, cardiac glycosides, saponins. Flavonoids, phenols, tannin content highest alata (0.27±0.0.002 mg: mg rutin per g extract, 10.63±0.0.017 gallic acid 6.72±0.06 mg/g respectively) followed V. amygdalina (0.20±00.002 8.27±0.0.017 7.98±0.03 respectively). While least all found curcas. Concentration dependent statistically significant difference observed both FRAP extracts. showed strongest amygdalina. Both that is not significantly (p>0.05) different from trolox. also demonstrated concentration manner. inhibition, S. exhibited most inhibitory among plant overall result study suggested amygdalina, phytochemicals, activities source constituents might be useful management diseases diabetes.